Masticin DC
200 mg Cefalexin + 340 mg Neomycin + 500 mg Cloxacillin + 10 000 IU Vitamin A
Intramammary suspension
One-step drying off and treatment of mastitis caused by bacteria sensitive to the active ingredients in cows at drying off. Masticin DC is formulated for cows that had long lactating period and/or suffered from mastitis right before drying-off.
Masticin DC is a combination of Cefalexin, Neomycin and Cloxacillin which exhibits prolonged bactericidal activity against most mastitis causing pathogens including penicillin-resistant strains. It provides an extended spectrum of efficacy against both Gram-negative and Gram-positive bacteria Streptococcus spp., Staphylococcus spp., (including Staphylococcus aureus), Corynebacterium pyogenes, Escherichia coli, Pseudomonas spp., Leptospira spp., Campylobacter foetus, Actinomyces spp., Clostridium spp.
Cefalexin represents a first generation cephalosporin and belongs to the class of ß-lactam antibiotics. It provides a mainly time-dependent antibacterial activity against Gram-positive pathogens by inhibiting the synthesis of the bacterial peptidoglycan cell wall.
Neomycin sulfate is a broad-spectrum first generation aminoglycoside antibiotic. It inhibits bacterial protein synthesis through irreversible binding to the 30 S ribosomal subunit of susceptible bacteria. Action of penicillins enhances uptake of aminoglycosides by bacterial cells.
Cloxacillin is a member of the Beta-lactam group and is active against penicillin G resistant staphylococci. It binds to membrane bound proteins known as PBP's (Penicillin-binding proteins) that are located beneath the cell wall, thereby disrupting cell walls synthesis. Cloxacillin is bactericidal.
Vitamin A takes part in redox reactions, stimulates regeneration of udder cisternal tissues and reduces impact of inflammation and helps maintain tissue integrity.
Active ingredients per one syringe (8 g) |
Cefalexin……………………..………..200 mg |
Dosage and administration |
For intramammary administration: infuse 1 syringe per quarter immediately after final milking. Treatment to be at least 45 days before calving.
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Withdrawal period |
Any animal treated with Masticin DC must not be slaughtered for food until 21 days after the last infusion. |
Presentation |
Polymer syringe of 8 g. |
Shelf life |
Shelf life of the veterinary medicinal product as packaged for sale: 2 years. |
Storage conditions |
Store in the original package between 5°C to 25°C, protected from light and moisture. |